Combine ground beef, Worcestershire sauce, garlic powder, and onion powder. Form 4 patties. Press a shallow indent in the center of each patty with your thumb to prevent doming.
Season the patties with salt and pepper on both sides.
Preheat a cast-iron skillet or griddle over medium-high heat. Cook the patties for 4 minutes per side. Do not press or move the patty during cooking. Internal temperature must reach 160°F / 71°C.
Add cheese in the last 60 seconds of cooking, cover the pan to melt.
Toast the buns cut-side down in the same pan for 1-2 minutes until golden.
Assemble the burgers: bottom bun, patty, cheese, lettuce, tomato, mayonnaise, ketchup, beef bacon, top bun.